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1.
Pakistan Journal of Pharmaceutical Sciences. 2018; 31 (5): 1813-1816
in English | IMEMR | ID: emr-199561

ABSTRACT

The phytochemical screening and antioxidant potential of bark and stem of Parthenocissus quinquefolia [L.]planch was assessed in order to verify its ethnopharmacological significance. All major secondary metabolites e.g. alkaloids, flavonoids, saponins, terpenoids, tannins, reducing sugars, cardiac glycosides and anthraquinones were present. Antioxidant activity was analysed by using five techniques which included DPPH Free Radical Scavenging Activity, FRAP [Ferric Reducing Antioxidant Power], TAA [Total Antioxidant Activity, TPC [Total Phenolic Content and MC [Metal Chelating] Activity. Ethanolic extract of bark showed the highest scavenging effects of 90.01+/-0.01%, with IC50 value of 24.32mg/ml. Aqueous stem extract showed best activity with IC50 value of 13.6+/-0.34mg/ml. The significance antioxidant potential indicates the effectiveness of bark and stem of P. quinquefolia in treatment of many diseases

2.
Pakistan Journal of Pharmaceutical Sciences. 2017; 30 (6): 2239-2245
in English | IMEMR | ID: emr-189736

ABSTRACT

In the present study the crude extracts of pollen of Centella asiatica [Linn.] Urban were explored for their antioxidant potential using Ferric Reducing Power, Metal Chelating Activity and Trolox Equivalent Antioxidant Capacity assays. In crude extracts of pollen antioxidant components were initially extracted in methanol and further fractionated in solvents of different polarity, such as n-Hexane, Chloroform, Ethyl Acetate and Water exhibited reasonable antioxidant activity. The extract was found to contain large amounts of phenolic and flavonoid contents ranged from 143-1155 mg/1 of gallic acid equivalent [GAE] and 911-2488 mg/1 of quercetin [QE] respectively. Moreover, Super oxide Anion Radical Scavenging Activity and GS-MS analysis were also carried out


Subject(s)
In Vitro Techniques , Phytochemicals , Plants, Medicinal , Plant Extracts , Phytotherapy , Antioxidants , Complex Mixtures , Gas Chromatography-Mass Spectrometry , Pollen
3.
Pakistan Journal of Pharmaceutical Sciences. 2014; 27 (2): 279-284
in English | IMEMR | ID: emr-138626

ABSTRACT

Antioxidant potential of the pollen of Typha domigensis Pers. using Ferric Reducing ower, Metal Chelating Activity and Trolox Equivalent Antioxidant Capacity [TEAC] assays has been carried out in the current research work. The antioxidant components were initially extracted from the pollen in methanol and were further fractionated in solvents of different polarity such as n-Hexane, Chloroform, Ethyl Acetate and Water. Methanol extract which was found to have high reducing power, total phenolic contents with high metal chelating activity, has considerable prospective to utilize as a natural antioxidant and be capable to link with the total phenolic contents of plant

4.
Pakistan Journal of Pharmaceutical Sciences. 2014; 27 (5): 1309-1315
in English | IMEMR | ID: emr-195090

ABSTRACT

The genera Suaeda and Salsola are halophytic plants belong to the family Chenopodiaceae. Species of these genera have been extensively used in traditional medicines against many diseases due to their various bioactive compounds such as carotenoids, vitamins, sterol, phenolic compounds etc


The present research was carried out to establish detailed pharmacognosy of Suaeda fruticosa, Suaeda monoica, Salsola imbricata and Salsola tragus, which included macroscopy, microscopy, physico-chemical parameters and qualitative phytochemical screening of leaf samples extracted with methanol and chloroform


It was observed that macroscopic and microscopic characteristics were diagnostic features and can be used for distinction and identification of these closely related plant species


Phytochemically, these plant species are rich in constituents like anthraquinones, alkaloids, carbohydrates, cardiac glycosides, flavonoids, saponins, phenolic compounds and terpenoids. Physico-chemical parameters revealed that in all investigated plant species; methanol extractive values were higher than that of chloroform


Moreover, total ash values were found to be higher than other acid insoluble and water-soluble ash values, while a considerable amount of moisture was present in the species of both genera. On the basis of pharmacognosy, species of Suaeda were found to be more promising than Salsola


Present investigation will contribute towards establishment of pharmacognostic profile of these medicinally effective plants species

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